Wednesday, 3 August 2022

Minimum pricing isn't working

Promises, promises

Minimum pricing of alcohol in Scotland is not going well. Self-styled public health advocates are baffled.

Now in its fifth year and facing a subset clause next year, the Scottish government’s own evaluation has made grim reading for those who claimed that setting a floor price of 50p on a unit of alcohol would be a game-changer in Scotland’s relationship with The Drink.  

 

.. no changes in the trend direction or statistically significant changes in the level of all alcohol-related crime and disorder

 
(Except in one local authority where alcohol-related crime went up.)
 
In the same month, a thorough evaluation of the impact of minimum pricing on alcohol-related A & E attendances was published. It found that the policy may have been associated with an increase in visits:
 

The odds ratio for an alcohol-related emergency department attendance following minimum unit pricing was 1.14 (95% confidence interval 0.90 to 1.44; p = 0.272). In absolute terms, we estimated that minimum unit pricing was associated with 258 more alcohol-related emergency department visits (95% confidence interval –191 to 707) across Scotland than would have been the case had minimum unit pricing not been implemented.

 
In June 2022, the evaluation looked at the heavy drinkers who were supposed to benefit most from minimum pricing. Its conclusions were unflinching: 
 

There is no clear evidence that MUP led to an overall reduction in alcohol consumption among people drinking at harmful levels or those with alcohol dependence, although some individuals did report reducing their consumption.

People drinking at harmful levels who struggled to afford the higher prices arising from MUP coped by using, and often intensifying, strategies they were familiar with from previous periods when alcohol was unaffordable for them. These strategies typically included obtaining extra money, while reducing alcohol consumption was a last resort.

MUP led to increased financial strain for a substantial minority of those with alcohol dependence as they obtained extra money via methods including reduced spending on food and utility bills, increased borrowing from family, friends or pawnbrokers, running down savings or other capital, and using foodbanks or other forms of charity.

Some people with alcohol dependence and their family members reported concerns about increased intoxication after they switched to consuming spirits rather than cider. In some of these cases, people also expressed concerns about increased violence. 

 

Alcohol-related hospital admissions refused to decline after the policy was introduced and alcohol-related deaths are at a nine-year high, although lockdowns doubtless had an affect on the latter. The policy cost Scottish drinkers £270 million in its first four years and all the SNP have to cling to is a modest drop in alcohol consumption, much of which is due to COVID-19.

Last month, a new piece of research was published in BMJ Open looking at alcohol consumption. It was not part of the official evaluation and was produced by academics who are very sympathetic to minimum pricing. They nevertheless struggled to make the policy look like a success.

Using Kantar survey data and comparing Scotland to northern England, they found that the introduction of minimum pricing was followed by a drop in consumption, as shown below.
 

It looks like an impressively steep decline until you realise that 5 grams of alcohol is barely half a unit. Per week. And the reduction in consumption from the off-trade, which is the only place minimum pricing makes any difference, was just 3 grams.

Moreover, the reduction in consumption was not evenly spread across the population. It was weighted towards women who tend to drink less anyway. 
 

The reductions in consumption are largely driven by women (a reduction of 8.6 g per week, 95% CI 2.9 to 14.3) rather than by men (a reduction of 3.3 g per week, 95% CI –3.6 to 10.4)

 
And among men who were the heaviest drinkers, consumption actually increased.
 

For the 95th percentile the introduction of MUP was associated with an increase in consumption for men of 13.8 g (95% CI 5.8 to 21.5), but not for women (4.8 g, 95% CI −4.0 to 13.7).

 
The study also contains bad news for the pub industry which, in classic Baptists and bootleggers fashion, supported minimum pricing for nakedly self-interested reasons.
 

For younger men there was an increase in off-trade consumption, which was offset by decreases in on-trade consumption in the same group.

 
I warned that this would happen five years ago. Leave people with less money in their pocket and they will have less to spend on the luxuries in life, like going to the pub.

None of these findings are terribly surprising to people who are more worldly than your average ‘public health’ academic. Raising the price of cheap booze was always more likely to change the behaviour of moderate tipplers than heavy drinkers. Hardcore drinkers were always going to find money to keep drinking and minimum pricing was never going to help the pub trade. It was only likely to make the poor poorer.

The authors of the study seem flabbergasted that a policy that had so much (naive and flawed) modelling behind it could turn out like it has.
 

When the Minister for Public Health, Sport and Wellbeing introduced the 2018 alcohol policy framework, he emphasised that the implementation of the MUP [minimum unit price] was strongly motivated by an interest in decreasing health inequalities through a reduction in alcohol consumption among the heaviest and most vulnerable drinkers. Our results indicate that this goal may not be fully realised…

 
You can say that again.
 

… first, we found that women, who are less heavy drinkers in our data and in almost all surveys worldwide to date, reduced their consumption more than men; second, the 5% of heaviest drinking men had an increase in consumption associated with MUP; and, third, younger men and men living in more deprived areas had no decrease in consumption associated with MUP. These results are surprising as modelling studies would have suggested otherwise.

 
It takes a heart of stone not to laugh at the best laid plans of philosopher kings falling apart at the seams.
 

We do not know why, for both younger men (those aged <32 years) and for those living in residential areas in the bottom two-fifths of deprivation, there was no decrease in consumption associated with MUP compared with older men and those living in less deprived areas.

 
One wonders if the authors have ever met any men aged under 32 or anyone in the bottom two-fifths of the income distribution. 
 

Several studies have found that overall, heavier drinkers— including people with alcohol use disorders—react less to price than the general population (ie, they react more price inelastic and their consumption is determined by other factors). However, while this may explain lower reductions, it cannot explain an increase in consumption.

 
Yes, that is a particularly awkward finding. Even I didn’t see that coming.
 

The results may also imply a diminished impact on alcohol-attributable hospitalisations and mortality, which have been shown to be strongly associated with heavy drinking in men and in those of lower socioeconomic status. Indeed, a large controlled study on emergency department visits following the introduction of MUP did not show any reduction in alcohol-related emergency department visits.

 
It’s fair to say that minimum pricing hasn’t gone the way that the likes of Dr Nick Sheron, a blowhard anti-alcohol campaigner, expected. In 2014, he insisted that minimum pricing was an ‘almost perfect alcohol policy because it targets cheap booze bought by very heavy drinkers and leaves moderate drinkers completely unaffected’. In the same year, Sir Ian Gilmore, chair of the Alcohol Health Alliance, described minimum pricing as an ‘evidence-based policy exquisitely targeted at those, and those around them, who are currently suffering harm’.

In a sensational act of hubris, three activist-academics published an article in 2017 claiming that the evidence-base for minimum pricing, a policy that had never been tried anywhere, fulfilled the great epidemiologist Austin Bradford Hill’s criteria for causality. It seemed absurd at the time and it seems almost grotesque now.

Still, this being ‘public health’, the answer to the medicine failing is to demand more of the same medicine.
 

If indeed the findings of our study are corroborated, then additional and/or different pricing mechanisms may need to be considered to reduce alcohol-attributable hospitalisations and mortality.

‘Tis but a flesh wound!

 

Postscript

While I was writing this post, I came across this new study which finds evidence of another unintended consequence which seems obvious to the man on the Clapham omnibus but never occurred to those who have qualifications in public health.
 

Following the introduction of MUP, total household food expenditure in Scotland declined by 1.0%, 95%CI [-1.9%, − 0.0%], and total food volume declined by 0.8%, 95%CI [-1.7%, 0.2%] compared to the north of England.

 
That might not necessarily be a bad thing. Scotland has an obesity problem, after all.
 

There is variation in response between product categories, with less spending on fruit and vegetables and increased spending on crisps and snacks.

 
Oh.


Tuesday, 2 August 2022

The fantasy world of public health modellers

Remember the study claiming that the Transport for London ban on 'junk food' advertising had let to London households consuming 1,000 fewer calories per week? It was execrable rubbish and now a study based on it is claiming that nearly 100,000 cases of obesity have been prevented by the ban.

It's all pure fantasy, as I say at Cap-X...
 

Regardless of what you think of this particular policy, it is worrying that public health policy-making has become so divorced from observable reality. Policies are proposed on the basis of modelling, evaluated on the basis of modelling, and the modelling is carried out by advocates of the policy. At no point are facts allowed to intrude. A rise in chocolate consumption becomes a fall in chocolate consumption. A rise in obesity becomes a fall in obesity. Activist-academics have created a world of pure imagination and are exploiting the broken peer-review process to drag us all into their land of make believe.

 
Do have a read. The 'public health' racket is so far down the rabbit hole it beggars belief.


Monday, 1 August 2022

Nicotine use, past and present

Earlier today I mentioned a study that is a go-to resource for e-cigarette evidence. I now present you with the definitive short-read about the future of nicotine written by Clive Bates.
 

So, here is the interesting question. What if nicotine use is no longer all that harmful? What if the real problem was always the inhalation of toxic smoke while trying to consume nicotine for its benefits? As early as 1991, the leading medical journal The Lancet reflected on how the nicotine landscape might look after the year 2000: “There is no compelling objection to the recreational and even addictive use of nicotine provided it is not shown to be physically, psychologically or socially harmful to the user or to others.”

In my view, we have reached the position where smoke-free nicotine products, such as e-cigarettes, heated tobacco, smokeless tobacco or nicotine pouches, can provide nicotine at acceptably low risk. By acceptably low risk, I don’t mean perfect safety, but within society’s normal risk appetites for consumption and other recreational activities. If continuing innovation in the design of the products ultimately leads to smoking cigarettes becoming obsolete, then the vast burden of smoking-related disease will decline and fade away.

 
Clive discusses five objections to safe nicotine use and shows why these arguments don't stack up. Do read it all.

 



E-cigarette facts and evidence

Colin Mendelsohn and colleagues have written a very nice response to a barking mad report commissioned by the Australian government about e-cigarettes. As you might expect from the Aussies, the report was a hatchet job on vaping. It made such claims as...

There is conclusive evidence that the use of e-cigarettes can cause respiratory disease 

(Based on the EVALI outbreak which had nothing to do with e-cigarettes.)

And...

There is strong evidence that never smokers who use e-cigarettes are on average around three times as likely than those who do not use e-cigarettes to initiate cigarette smoking.

(A claim that ignores the large decline in smoking rates among young people since vaping went mainstream and ignores common liability.)
 
Mendelsohn et al. conclude that:
 
Contrary to the conclusions of the Banks review, the evidence suggests that vaping nicotine is an effective smoking cessation aid; that vaping is substantially less harmful than smoking tobacco; that vaping is diverting young people away from smoking; and that vaping by smokers is likely to have a major net public health benefit if widely available to adult Australian smokers.

I doubt that this will come as a surprise to readers of this blog. The main reason I recommend the article is not for its conclusion but because it is a succinct summary of the evidence. 
 
It is difficult to keep up with e-cigarette research. More than 50 studies are published every week and a lot of it is junk science from the USA. Mendelsohn et al. is a handy, up-to-date reference point for anyone who wants to find the key studies on the main issues of risk, smoking cessation, the 'gateway' effect, the EVALI nonsense, etc.

It's one to keep in your back pocket if faced with spurious arguments against vaping. It's paywalled but I daresay the authors will give you access if you ask them on ResearchGate


UPDATE

Within minutes of posted this, I saw on Twitter that the lead author of the Aussie report has been given an award. Because of course she did.